Figure 2
From: The role of Src kinase in the biology and pathogenesis of Acanthamoeba castellanii
Inhibition of Src kinase blocks A. castellanii phagocytosis. The effects of Src kinase in the ability of A. castellanii to uptake live non-invasive E. coli strain, HB101. Untreated A. castellanii were used as 100% phagocytosis and levels of phagocytosis in inhibitor-treated A. castellanii are shown as percentage change. Note that Src kinase inhibitor, PP2 but not its inactive analog, PP3 exhibits a significant decrease in A. castellanii phagocytosis at 50 μM (P < 0.05). Results represent the mean of three independent experiments performed in duplicate, bars represent standard error.