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Table 5 The remaining percentage (± standard deviation) of the imidacloprid and flumethrin start amount in 177 collars worn by laboratory cats and dogs for different durations

From: The synergistic action of imidacloprid and flumethrin and their release kinetics from collars applied for ectoparasite control in dogs and cats

Bayer Animal Health Study number

No. of animals

Wearing time [days]

mean % of initial amount

   

Imidacloprid

Flumethrin

CAT STUDIES = small collar

ID 35118

3

2

94.6 ± 0.67

99.7 ± 0.79

 

3

7

89.6 ± 0.48

98.3 ± 0.44

 

3

14

85.5 ± 4.32

97.0 ± 1.25

 

3

28

81.7 ± 1.32

97.7 ± 0.75

 

3

56

72.6 ± 2.61

95.0 ± 0.22

 

3

84

70.9 ± 1.81

91.7 ± 2.27

ID 35638

8

30

79.7 ± 2.95

97.0 ± 0.64

ID 33697

30

60

77.7 ± 8.30

92.5 ± 3.13

ID 35121

8

238

74.7 ± 4.53

81.6 ± 5.39

ID 35635

10

241

61.4 ± 2.50

72.7 ± 2.52

ID 35632

10

240

57.9 ± 3.27

85.6 ± 2.28

ID 35630

9

238

59.7 ± 3.12

84.9 ± 2.23

mean cat 8 months

37

238-240

59.7 ± 3.0

81.9 ± 6.0

DOG STUDIES = large collar

ID 35637

8

30

81.7 ± 2.23

96.5 ± 2.97

ID 33692

32

60

79.1 ± 4.62

97.7 ± 2.71

ID 33691

10

90

74.7 ± 4.53

81.6 ± 5.39

ID 35117

6

91

72.0 ± 2.32

88.8 ± 5.92

ID 35631

10

245

60.5 ± 3.96

80.8 ± 5.44

ID 35120

8

238

62.4 ± 6.21

70.4 ± 3.47

ID 35636

10

240

68.7 ± 2.03

80.8 ± 7.40

Mean dog 8 months

28

238-245

64.0 ± 5.40

77.8 ± 7.2

Mean total 8 months

65

238-245

61.6 ± 4.70

80.1 ± 6.9