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Table 1 Summary of recent deep learning approaches in automated malaria diagnostic systems

From: An optimised YOLOv4 deep learning model for efficient malarial cell detection in thin blood smear images

Author

Database

Plasmodium species

Classification

Technique

Results

Sriporn et al. [18]

NLM, 7000 cell images

P. falciparum

Binary

Xception, Inception-V3,ResNet-50,NasNetMobile,VGG-16, AlexNet

Best performing model: Xception

Accuracy: 99.28%

Precision: 99.29%

Recall: 99.29%

F1-Score: 99.28%

Umer et al. [19]

NLM, 27558 cell images (150 infected, 50 healthy patients)

P. falciparum

Binary

Customised CNN

Accuracy: 99.96%

Precision: 100%

Recall: 99.93%

Zhao et al. [20]

NLM, 27558 cell images (150 infected, 50 healthy patients)

Broad Institute dataset contains 1364 blood smear images with 80,000 infected cells

P. falciparum

P.vivax

Binary

ResNet50V2, VGG16, VGG19,

InceptionV3, DenseNet121,

MobileNetV2

Best performing model: VGG-16

Accuracy: 96.53%

Sensitivity: 95.0%

Specificity: 98.07%

AUC: 99.40%

F1-Score: 96.48%

MCC: 93.30%

Cross-dataset:

AUC:94.5%

Ragb et al. [21]

NLM, 27,558 cell images (150 infected, 50 healthy patients)

P. falciparum

Binary

SqueezeNet, MobileNetV2, GoogleNet, ResNet18, DarkNet19, InceptionV3, AlexNet, Xception, AlexNet,

DenseNet201, ResNet101, VGG19, Ensembled model

Best performing model: Ensembled model

Sensitivity: 97.94%

Specificity: 97.78%

Precision: 97.8%

Cinar et al. [22]

NLM, 27558 cell images (150 infected, 50 healthy patients)

P. falciparum

Binary

AlexNet, ResNet50, DenseNet201, VGG19, GoogleNet, InceptionV3

Best performing model: DenseNet201

Accuracy: 97.83%

Maqsood et al. [23]

NLM, 27558 cell images (150 infected, 50 healthy patients)

P. falciparum

Binary

VGG16, VGG19, Xception, Densenet121, Densenet169, Densenet201,

Inceptionv3, InceptionResnet_v2, Resnet50, Resnet101, Resnet152, SqueezeNet, Customised CNN

Specificity: 97.78%

sensitivity: 96.33%

Precision: 96.82%

Accuracy: 96.82%

F1-Score: 96.82%

MCC: 93.64%

Diyasa et al. [24]

NLM, 27,558 cell images (150 infected, 50 healthy patients)

P. falciparum

Binary

GoogleNet

Accuracy:93.89%

Loddo et al. [25]

NLM, 27558 cell images (150 infected, 50 healthy patients)

MP-IDB, 229 images

P. falciparum

P. vivax

Binary and Multi-class

AlexNet, DenseNet-201,

ResNet-18, ResNet-50, ResNet101, GoogleNet, ShuffleNet, SqueezeNet,MobileNetV2, Inceptionv3, VGG-16

Best performing models

Binary: ResNet-18

Accuray: 97.68%

Multi-class:

DenseNet-201:

Accuracy: 99.40%

Cross-dataset validation:

Accuracy: 97.45%

Shambhu et al. [26]

NLM, 27558 cell images (150 infected, 50 healthy patients)

P. falciparum

Binary

Customised CNN

96.02%

Vijayalaskhmi et al. [27]

1030 infected images and 1520 non-infected images

P. falciparum

Binary

LeNet-5, AlexNet, GoogleLeNet, VGG16, VGG19

Best performing model: VGG19

Sensitivity: 93.44%

Specificity: 92.92%

Precision: 92.92%

Accuracy: 93.13%

F1-Score: 93.13%

Arshad et al. [28]

IML-malaria

P. vivax

Multi-class

VGG16, VGG19, ResNet50V2,

DenseNet169, DenseNet201

Best performing model: ResNet-50v2:

79.61%

Rahman et al. [29]

BBBC041V1:1364 images

MP-IDB:229 images

P. falciparum

P. vivax

Binary

VGG-16,VGG-19, Xception, ResNet-50, customised CNN

Best performing model: VGG19

Accuracy: 99.35%

F1-Score: 96.85%

Sensitivity: 92.31%

Specificity: 99.76%

AUC: 96.03%

Cross Dataset validation:

Accuracy: 85.18%

Sensitivity: 70.19%

Specificity: 100%

F1-Score: 84.82%

AUC: 85.09%

Yang et al. [30]

2567 thin blood smear images

P. vivax

Binary

YOLOv2

79.22%

Krishnadas et al. [31]

MP-IDB

P. falciparum

P. vivax

P. malariae

P. ovale

Multi-class

Yolov5 and Scaled Yolov4

Best performing model: Scaled Yolov4

Parasite classification: Accuracy: 83%

Sukumarran et al. [32]

MP-IDB and Malaria Research Centre, Unimas Sarawak

P. falciparum

P. vivax

P. malariae

P. ovale

P. knowlesi

Binary

YOLOv4, Faster R-CNN, SSD-300

Best performing model: YOLOv4

mAP: 93.87%

Cross dataset:

mAP: 84.04%

  1. BBBC Broad Bioimage Benchmark Collection, CNN convolutional neural network, MP-IDB Malaria Parasite Image Database, NLM National Library of Medicine, YOLO You Only Look Once object detection algorithm