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Fig.2 | Parasites & Vectors

Fig.2

From: Inhibition of Foxp3 expression in the placenta of mice infected intraperitoneally by toxoplasma gondii tachyzoites: insights into the PPARγ/miR-7b-5p/Sp1 signaling pathway

Fig.2

T. gondii antigens downregulated Foxp3 but upregulated miRNA-7b and miRNA-16 in vitro. a Foxp3 expression in EL4 cells stimulated by ESA for 24 h was assayed by western blot. b mRNA level of Foxp3 in EL4 cells stimulated by ESA for 12 h was determined by real-time PCR. c microRNAs in EL4 cells at 12 h post-stimulation of ESA were assayed by real-time PCR. Con: Control; ESA: T. gondii excreted-secreted antigens; Data were representative of the results of three independent experiments (mean ± SD). Statistical analysis was conducted using two-tailed unpaired Student’s t-test. *: P < 0.05; n.s.: P > 0.05

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Parasites & Vectors

ISSN: 1756-3305

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