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Fig. 3 | Parasites & Vectors

Fig. 3

From: Inhibition of Foxp3 expression in the placenta of mice infected intraperitoneally by toxoplasma gondii tachyzoites: insights into the PPARγ/miR-7b-5p/Sp1 signaling pathway

Fig. 3

miR-7b inhibited Foxp3 expression. a Foxp3 expression was assessed by using western blot in EL4 cells that were transfected with mimics or inhibitors (NC-mi, miR-7b-mi, NC-i, and miR-7b-i), respectively. NC-mi: negative controls of miRNA mimics; miR-7b-mi: microRNA-7b mimics; NC-i: negative controls of miRNA inhibitors. miR-7b-i: microRNA-7b inhibitors. b Foxp3 expression was detected by using western blot in EL4 cells transfected with mimics or inhibitors (NC-mi, NC-i, miR-16-mi, and miR-16-i), respectively. miR-16-mi: microRNA-16 mimics; miR-16-i: microRNA-16 inhibitors. Data were representative of the results of three independent experiments (mean ± SD). Statistical analysis was conducted using two-way ANOVA with Sidak’s multiple comparisons test (a and b). *: P < 0.05. n.s.: P > 0.05

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Parasites & Vectors

ISSN: 1756-3305

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