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Fig. 6 | Parasites & Vectors

Fig. 6

From: Inhibition of Foxp3 expression in the placenta of mice infected intraperitoneally by toxoplasma gondii tachyzoites: insights into the PPARγ/miR-7b-5p/Sp1 signaling pathway

Fig. 6

miR-7b suppressed Sp1 expression. a Sp1 expression was assessed by using western blot analysis in EL4 cells stimulated by ESA for 24 h in vitro. b Sp1 expression was detected by using western blot after 48 h-transfection in EL4 cells that were transfected with NC-mi or miR-7b-mi, respectively. NC-mi: negative controls of miRNA mimics; miR-7b-mi: microRNA-7b mimics. c Sp1 expression was detected by using western blot in EL4 cells that were transfected with NC-i or miR-7b-i. NC-i: negative controls of miRNA inhibitors; miR-7b-i: microRNA-7b inhibitors; ESA: T. gondii excreted-secreted antigens. Data were representative of the results of three independent experiments (mean ± SD). Statistical analysis was conducted using two-tailed unpaired Student’s t-test (a), or one-way ANOVA Tukey’s multiple comparisons test (b and c). *: P < 0.05. n.s.: P > 0.05

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Parasites & Vectors

ISSN: 1756-3305

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