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Table 2 Results of multilevel model for each of the variables measured.

From: UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle

 

Mff+

Nodule diameter+

♂/nodule#

♀MOT#

♀OD492+

Interaction (time*trtgrp)

<0.001

<0.001

ND

ND

0.054

Fixed effect (time)

<0.001

<0.001

ND

ND

0.001

Individual treatments compared to controls at 24 weeks

150 mg/kg UMF 078 im

0.005

0.002

0.001

<0.001

<0.001

50 mg/kg UMF 078 im

0.481

0.679

0.006

0.103

0.008

150 mg/kg UMF 078 ia

0.729

0.789

0.927

0.952

0.179

50 mg/kg UMF 078 ia

0.155

0.347

0.189

0.482

0.858

  1. These were run using the gllamm procedure in STATA9 with either a linear(+) error structure and a random intercept, non parametric Kruskal Wallis ANOVA (#).