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Figure 1 | Parasites & Vectors

Figure 1

From: Mathematical models for lymphatic filariasis transmission and control: Challenges and prospects

Figure 1

Reduction in microfilaraemia load (efficacy) following repeated treatments with single (A) or combination therapies (B) with antifilarial drugs. Data are from filed trials in India [31]. Dots are observations and the lines are based on the fitting of non-linear function of the form y = a x ( 1 + b x ) MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGacaGaaiaabeqaaeqabiWaaaGcbaGaemyEaKNaeyypa0tcfa4aaSGaaeaacqWGHbqycqWG4baEaeaadaqadaqaaiabigdaXiabgUcaRiabdkgaIjabdIha4bGaayjkaiaawMcaaaaaaaa@37D9@ with y being the efficacy after x number of treatments. The parameter a measures the initial rate of increase of y with x, and y reaches a saturation level b', with b ' = b c MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGacaGaaiaabeqaaeqabiWaaaGcbaGaemOyaiMaei4jaCIaeyypa0tcfa4aaSGaaeaacqWGIbGyaeaacqWGJbWyaaaaaa@3238@ .

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