From: Trichinella spiralis: nurse cell formation with emphasis on analogy to muscle cell repair
Gene Name | Description | Expression change | |
---|---|---|---|
 |  | Ts | Tp a |
tumor necrosis factor receptor 1 (TNFR1) | TNF-medicated apoptosis | ↑ | ↑ |
proline dehydrogenase (oxidase) 2 (Prodh2) | mitochondria-mediated apoptosis | ↑ | ↑ |
Bcl2-interacting killer-like (Biklk) | Bcl family protein; induction of apoptosis | ↑ | ↑ |
B-cell leukemia/lymphoma 6 (Bcl6) | apoptosis; caspase activation | ↑ | ↑ |
programmed cell death protein 11 (Pdcd11) | hydrolase activity; apoptosis | ↑ | ↑ |
clusterin (CLU) | anti- or proapoptotic activity | ↑ | ↑ |
nuclear protein 1 (Nupr1) | induction of apoptosis; response to stress | ↑ | NC b |
p53 | apoptosis, DNA repair, cell cycle arrest | ↑ | ↑ |
p21 | apoptosis, cell cycle arrest | ↑ | ↑ |
MDM2 | apoptosis, negative regulator of p53 | ↑ | ↑ |
Bcl-2 associated protein X (BAX) | mitochondria-medicated apoptosis | ↑ | ↑ |
Apoptotic protease activating factor 1 (Apaf1) | mitochondria-medicated apoptosis | ↑ | ↑ |
Caspase 9 | mitochondria-medicated apoptosis | ↑ | ↑ |
protein kinase B (PKB) | promote cell survival and prevent apoptosis | ↑ | ↑ |
tumor necrosis factor-alpha (TNF) | cell proliferation, differentiation, apoptosis | ↑ | UR c |
TNFR1-associated via death domain (TRADD) | adaptor of TNFR1 mediated apoptosis | ↑ | UR |
Caspase 8 | apoptosis | ↑ | UR |
Caspase 3 | apoptosis | ↑ | UR |
TNF receptor-associated factor 2 (Traf2) | mediator of anti-apoptotic in TNFR1 signal | ↑ | UR |
Receptor interactive protein (RIP) | mediator of anti-apoptotic in TNFR1 signal | ↑ | UR |