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Table 1 LC50 and LC100 values of disinfectants and water for bloodstream forms of T. brucei, epimastigotes of T. rangeli and promastigotes of Leishmania major.

From: Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites

 

T. brucei

T. rangeli

L. major

Reagent

LC50

LC100

LC50

LC100

LC50

LC100

Bleach *

0.019

0.05

0.016

0.05

0.021

0.05

Trigene

0.134

0.2

0.037

0.2

0.029

0.2

Ethanol

10.6

15

13.2

17.5

10.9

15

Soap†

0.068

0.1

0.035

0.1

0.063

0.1

Water

64

80

72

90

65

90

  1. LC50 and LC100 values are presented in %. Each value represents the mean of three independent experiments. Standard deviations were less than 10%. LC50, 50% lethal concentration; LC100, 100% lethal concentration.
  2. * As NaOCl. In aqueous solutions, NaOCl forms NaOH and HOCl (hypochlorous acid). HOCl is the active reagent what kills pathogens and is referred to as available chlorine. At a pH of ~7 and at room temperature, 80% of the chlorine is in the available form (HOCl) [10]. For example, 0.05% bleach equals 0.05% NaOCl which produces around 0.04% HOCl.
  3. †Liquid hand soap.
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Parasites & Vectors

ISSN: 1756-3305

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