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Table 1 Repellent effects of different DDA-based lotion-formulations against I. ricinus nymphs (MO-bioassay)

From: Prevention of infectious tick-borne diseases in humans: Comparative studies of the repellency of different dodecanoic acid-formulations against Ixodes ricinus ticks (Acari: Ixodidae)

Project

Crawling to the tip of the glass rod

Attaching the filter paper on the drum

Dropping off the attachment site

Repellency [%]

 

n

%

n

%

n

%

Significance*

 

Trial 1

        

   Blank test

29

96.7

27

93.1

0

0

  

   10% DDS

30

100

28

93.3

25

89.3

p < 0.001

88.90

   Batch 030138

30

100

23

76.7

22

95.7

p < 0.001

96.30

   Batch 030142

29

96.7

20

69.0

15

75.0

p < 0.001

81.40

Trial 2

        

   Blank test

29/30

96.7

24/27

82.8/90.0

0/1

0/3.7

  

   10% DDS

30

100

24

80.0

21

87.5

p < 0.001

88.5

   Batch 030174

30

100

20

66.7

17

85.0

p < 0.001

87.5

   Batch 030175

29/29

96.7/96.7

21/20

72.4/69.0

19/17

90.5/85.0

p < 0.001

91.63/88.5

   Batch 030176

28

93.3

22

78.6

20

90.9

p < 0.001

91.63

Trial 3

        

   Blank test

30

100

28

93.3

0

0

  

   10% DDS

30

100

24

80.0

19

79.2

p < 0.001

82.10

   Batch 040088

30

100

23

76.7

19

82.6

p < 0.001

85.74

Trial 4

        

   Blank test

30

100

29

96.7

0

0

  

   Batch 040108

30

100

21

70.0

21

100

p < 0.001

100

   Batch 050030

30

100

24

80.0

24

100

p < 0.001

100

  1. The quantity of repellent applied per test was about 1 mg/cm2, corresponding to approximately 0.1 mg DDA/cm2. Batch No. 050030 is identical to the final product ContraZeck® in terms of the qualitative and quantitative ingredients and fragrances. Batch No. 040088 and Batch No. 040108 are identical in terms of the qualitative and quantitative ingredients and fragrances. *Significance in relation to blank test