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Figure 3 | Parasites & Vectors

Figure 3

From: Blood feeding by the Rocky Mountain spotted fever vector, Dermacentor andersoni, induces interleukin-4 expression by cognate antigen responding CD4+ T cells

Figure 3

Intradermal injection of female or male Dermacentor andersoni derived salivary gland extract (SGE) programs TCR Tg CD4+ T cells to express IL-4. Panel A, representative histograms of CFSE dilution. Panel B, quantitation of CFSE dilution. Panel C depicts representative intracellular staining for IFN-γ vs IL-4 expression. Panel D, quantitation of cytokine expression. For panels B and D, asterisks indicate P < 0.05 compared to uninfested controls. N = 4 mice per group.

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