Intradermal injection of female or male Dermacentor andersoni derived salivary gland extract (SGE) programs TCR Tg CD4+ T cells to express IL-4. Panel A, representative histograms of CFSE dilution. Panel B, quantitation of CFSE dilution. Panel C depicts representative intracellular staining for IFN-γ vs IL-4 expression. Panel D, quantitation of cytokine expression. For panels B and D, asterisks indicate P < 0.05 compared to uninfested controls. N = 4 mice per group.