Table 2 Comparison of assays for the effect of chloroquine (CQ) on ΔΨm in Plasmodium falciparum.
Plasmodium falciparum strain | Chloroquine concentration | Chloroquine incubation time | Probe | Affect on ΔΨm | Reference |
|---|---|---|---|---|---|
F32 (CQ sensitive) | 20 nM | 20 min | DiOC6(3) | No effect | Nyakeriga et al. [39] |
3D7 (CQ sensitive) 7G8 (CQ resistant) | 55 nM 1400 nM | 18 h 18 h | JC-1 JC-1 | Sig. loss Not sig. | Meslin et al. [14] |
3D7 (CQ sensitive) 7G8 (CQ resistant) K1 (CQ resistant) | >3 μM >3 μM >12 μM | 4 h >8 h >8 h | JC-1 JC-1 JC-1 | Sig. loss Sig. loss Sig. loss | Ch'ng et al. [37] |