Figure 5From: The nature and combination of subunits used in epitope-based Schistosoma japonicum vaccine formulations affect their efficacyHistopathology of egg granulomas in the livers. (A) Six weeks after challenge, mice were sacrificed. After portal perfusion, livers were dissected and stained with H&E for microscopic examination. The number of granulomas in the liver of each mouse was counted in 10 random fields and the data are expressed as the mean ± SD of 16 mice (8 mice/group) from two independent experiments. (B) The size of nonconfluent granulomas formed around a single egg was assessed using a video micrometer. The data are expressed as the mean ± SD of 16 mice (8 mice/group) from two independent experiments. *P < 0.05, compared to the 18K-PDDV and PBS groups.Back to article page