Figure 2

Domain prediction of bovipain-2. Putative functional domains in bovipain-2 were predicted based on the amino acid sequence of the T2B strain. The numbers indicate the eukaryotic thiol (cysteine) proteases cysteine (1); histidine (2) and asparagine (3) catalytic regions. Amino acids in bold represent active sites (Q254, C260, H389, N411). Sequence alignments of these three regions in several Babesia, Theileria and Plasmodium spp. are shown. Arrows indicate amino acids of the active site.