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Table 1 A comparison of the characteristics of immunomics protein microarrays with conventional proteomic approaches

From: Schistosomiasis vaccine discovery using immunomics

Characteristic Protein Microarrays Conventional Proteomic Approaches
Protein Structure Can be limited Present, depending on methods
Protein Abundance Not affected Low abundance proteins lost
Protein Identification Not affected Difficult
Pathogen Protein Extraction Not applicable (uses DNA/cDNA) Difficult
Protein localisation Not affected Membrane proteins difficult to extract and detect
Technical difficulty Low High