Figure 4

Amoxicillin killing of various Salmonella strains adhering to schistosomes. Salmonella and Schistosoma were co-incubated, exposed to 32 μg/ml of amoxicillin, recovered and enumerated as described above. Data presented are the percentages of Salmonella killed or inhibited by antibiotics prior to incubation with schistosomes (open boxes) or in the presence of Schistosoma (black boxes). Bacterial survival was significantly higher (p <0.01) during adherence to schistosomes for Salmonella expressing the FimH that confers mammalian cell adherence. No significant differences were noted for survival of bacteria prior to schistosome attachment, following attachment to schistosomes, in the presence of HEp-2 cells, or in the presence of Girardia (data not shown).