|
Day 0
|
Day 7
|
Day 14
|
Day 21
|
Day 28
|
---|
Treatment
1
|
Mean # of fleas
2,3
|
% efficacy
4
|
Mean # of fleas
|
% efficacy
|
Mean # of fleas
|
% efficacy
|
Mean # of fleas
|
% efficacy
|
Mean # of fleas
|
% efficacy
|
12 hours post-treatment or infestation
| | | | | | | | | | |
Controls
|
52.2a
| |
62.2a
| |
56.4a
| |
47.5a
| |
48.4a
| |
Selamectin
|
16.0b
|
69.4
|
0.6b
|
99.1
|
5.3b
|
90.6
|
18.6a
|
60.9
|
20.6a
|
57.3
|
Imidacloprid-Moxidectin
|
0.0c
|
100.0
|
0.0c
|
100.0
|
0.2c
|
99.7
|
0.7b
|
98.5
|
4.7b
|
90.2
|
24 hours post-treatment or infestation
| | | | | | | | | | |
Controls
|
45.1a
| |
56.3a
| |
52.4a
| |
47.1a
| |
49.6a
| |
Selamectin
|
1.6b
|
96.4
|
0.0b
|
100.0
|
0.1b
|
99.7
|
0.5b
|
99.0
|
2.3b
|
95.3
|
Imidacloprid-Moxidectin
|
0.0c
|
100.0
|
0.0b
|
100.0
|
0.1b
|
99.8
|
0.0b
|
100.0
|
1.2b
|
97.5
|
- 1Each of 8 cats in the control group received no treatment. Each of 8 cats in the 10% w/v imidacloprid + 1.0% w/v moxidectin or selamectin (6%w/v) treatment groups were administered the topical spot-ons, according to label directions on Day 0.
- 2Each cat was infested with 100 adult Ctenocephalides felis from the KS1 strain on days -2, 7, 14, 21 and 28.
- 3Geometric mean # of fleas recovered from cats per treatment group.
- 4% efficacy = ((geometric mean count control -geometric mean count treatment)/geometric mean count treatment) × 100
- a, b, c geometric means within a column with unlike letter superscripts are significantly different (P < 0.05).