A diagnostic challenge for schistosomiasis japonica in China: consequences on praziquantel-based morbidity control

Table 1 Sensitivity, specificity and predictive value of KK and MHT methods for diagnosing S. japonicum infection

Method	Sensitivity (%)	Specificity (%)	*PPV (%)	*NPV (%)	*Prevalence (%)	Reference gold standard	Author and date of publication
*KK	51.1-84.1	100	100	93.2-96.5	13.0-18.4	two repeated KK results (6 slides)	Lin et al. 2008 [13]
	59.6-70.0	100	100	93.3-97.9	6.6-18.6	two repeated KK results (6 slides)	Zhou et al. 2007 [14]
	72.2-100.0	100	100	96.3-100.0	6.2-12.0	combined results of KK(3 slides) and MHT	Xu et al. 2007 [15]
	58.3	100	100	83.5	32.1	MHT	He et al. 2007 [16]
	67.6	100	100	58.9	68.3	seven repeated KK examinations (14 slides)	Yu et al. 2007 [17]
	69.9	100	100	95.63	13.2	combined results of KK(3 slides) and MHT	Zhu et al. 2005 [18]
	50.0	100	100	98.02	3.9	combined results of KK(3 slides) and MHT	Song et al. 2003 [19]
	40-68	100	100	52.5-80.5	36.0-68.3	seven accumulated KK results(14 slides)	Yu et al. 1998 [20]
*MHT	24.0-95.0	100	100	95.2-99.6	6.2-12.0	combined results of KK (3 slides) and MHT	Xu et al.2007 [15]
	79.2	100	100	94.0	23.6	KK(3 slides)	He et al. 2007 [16]
	32.8	100	100	40.9	68.3	seven accumulated KK results (14 slides)	Yu et al. 2007 [17]
	89.8	100	100	98.5	13.2	combined results of KK(3 slides) and MHT	Zhu et al.2005 [18]
	94.4	100	100	99.8	3.9	combined results of KK(3 slides) and MHT	Song et al. 2003 [19]

*PPV = Positive predictive value; *NPV = Negative predictive value; *KK = The Kato-Katz thick smear stool examination; *MHT = Miracidium hatching test;
*Prevalence is calculated based on the reference gold standard

ISSN: 1756-3305