Table 2 Sensitivity, specificity and predictive value of COPT and IHA methods for diagnosing S. japonicum infection
Method | Sensitivity (%) | Specificity (%) | *PPV (%) | *NPV (%) | *Prevalence (%) | Reference gold standard | Author and date of publication |
|---|---|---|---|---|---|---|---|
*COPT | 85.8 | 54.1 | 36.6 | 92.5 | 23.6 | KK (3 slides) | He et al. 2007 [16] |
| Â | 82.8 | 57.7 | 48.1 | 87.7 | 32.1 | MHT | He et al. 2007 [16] |
| Â | 85.2 | 95.6 | 74.9 | 97.7 | 13.4 | MHT | Zhu et al. 2005 [26] |
| Â | 72.2 | 93.7 | 31.7 | 98.8 | 3.9 | combined results of KK (3 slides) and MHT | Song et al. 2003 [19] |
*IHA | 80.0 | 93.6 | 18.8 | 99.6 | 1.7 | MHT | Zhang et al. 2010 [27] |
| Â | 69.7 | 89.4 | 36.8 | 96.8 | 8.9 | two repeated KK results (12 slides) | Lin et al. 2008 [28] |
| Â | 97-100 | 60-77 | 19-30 | 100.0 | 3.1-14.2 | KK examination (3 slides) | Zhou et al. 2008 [29] |
| Â | 83.7-92.3 | 55.8-67.3 | 16.6-30.2 | 93.7-99.2 | 6.6-18.6 | two repeated KK results (6 slides) | Zhou et al. 2007 [14] |
| Â | 76.0-85.6 | 35.7-63.6 | 8.9-22.2 | 94.8-97.7 | 6.2-12.0 | combined results of KK (3 slides) and MHT | Xu et al. 2007 [15] |
| Â | 80.3 | 48.4 | 77.0 | 53.3 | 68.3 | seven repeated KK examinations (14 slides) | Yu et al. 2007 [17] |
| Â | 66.7-100.0 | 67.6-91.6 | 2.9-15.8 | 97.6-100.0 | 0.3-5.7 | two repeated KK results (6 slides) | Wang et al.2006 [30] |
| Â | 82.1 | 71.1 | 26.8 | 96.9 | 9.2 | KK (3 slides) | Li et al. 2002 [31] |