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Table 2 Amino acid substitutions of Pvs28 from Yunnan P. vivax isolates

From: Genetic diversity of transmission-blocking vaccine candidates Pvs25 and Pvs28 in Plasmodium vivax isolates from Yunnan Province, China

Haplotypes (number) SS EGF-1 EGF-2 EGF-2 EGF-3 EGF-3 RR RR THR
  14 52 98 105 116 140 179 # 222
Sal-I V M L E L T G 6 I
Pvs28-I (n = 19) L S 5/6
Pvs28-II (n = 4) I V 6
Pvs28-III (n = 2) L K V 6
Pvs28-IV (n = 2) L 6
Pvs28-V (n = 1) 6 M
Pvs28-VI (n = 1) V 6 M
Pvs28-VII (n = 1) L E 6
  1. SS, secretary signal sequence; EGF, epidermal growth factor-like domain; RR, repeat regions, # indicates the number of the GSGGE/D repeats; THR, the C terminal hydrophobic region.
  2. • indicates identical amino acid residues compared to the Salvador I strain.