TY - JOUR AU - Genes, Carlos AU - Baquero, Eduard AU - Echeverri, Fernando AU - Maya, Juan D. AU - Triana, Omar PY - 2011 DA - 2011/05/06 TI - Mitochondrial dysfunction in Trypanosoma cruzi: the role of Serratia marcescens prodigiosin in the alternative treatment of Chagas disease JO - Parasites & Vectors SP - 66 VL - 4 IS - 1 AB - Chagas disease is a health threat for many people, mostly those living in Latin America. One of the most important problems in treatment is the limitation of existing drugs. Prodigiosin, produced by Serratia marcescens (Rhodnius prolixus endosymbiont), belongs to the red-pigmented bacterial prodiginine family, which displays numerous biological activities, including antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties. Here we describe its effects on Trypanosoma cruzi mitochondria belonging to Tc I and Tc II. SN - 1756-3305 UR - https://doi.org/10.1186/1756-3305-4-66 DO - 10.1186/1756-3305-4-66 ID - Genes2011 ER -