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Table 1 Schematic Experimental Design of studies aimed at testing the efficacy of an imidacloprid 10.5%/flumethrin 4.5% collar against ectoparasites on dogs

From: Efficacy of an imidacloprid/flumethrin collar against fleas, ticks, mites and lice on dogs

Study Day (Week) Activity
−10 (approximately) Acclimatization to housing
−7 Pre-study flea or tick infestations
−4 Select dogs with highest flea or tick counts, and allocate them to treatment groups consisting of at least 7 untreated dogs and 7 treated dogs
−2 Tick infestation
- 1 Flea infestation
0 Fit collars to all dogs in treatment group
2 Flea and tick counts
7 (=Week 1) Flea and/or tick infestation
8, 9 Flea counts Day 8, tick counts Day 9
28 (=Week 4) Flea and/or tick infestation
29, 30 Flea counts Day 29, tick counts Day 30
56 (=Week 8) Flea and/or tick infestation
57, 58 Flea counts Day 57, tick counts Day 58
84 (=Week 12) Flea and/or tick infestation
85, 86 Flea counts Day 85, tick counts Day 86
112 (=Week 16) Flea and/or tick infestation
113, 114 Flea counts Day113, tick counts Day 114
140 (=Week 20) Flea and/or tick infestation
141, 142 Flea counts Day 142, tick counts Day 142
168 (=Week 24) Flea and/or tick infestation
169, 170 Flea counts Day 169, tick counts Day 170
196 (=Week 28) Flea and/or tick infestation
197, 198 Flea counts Day 197, tick counts Day 198
224 (=Week 32) Flea and/or tick infestation
225, 226 Flea counts Day 225, tick counts Day 226
238 (=Week 34) Flea and/or tick infestation
239, 240 Flea counts Day 239, tick counts Day 240