Src kinase inhibitor, PP2 exhibited amoebistatic effects. A. castellanii were incubated in the presence of Src kinase-specific inhibitor, PP2 or its inactive analog, PP3 in normal growth medium (PYG) for various intervals of time. Cell numbers were determined using haemocytometer counting. Micromolar concentrations of PP2 but not PP3 abolished amoebae growth. Results represent the mean of three independent experiments performed in duplicate, bars represent standard error.