Inhibition of Src kinase blocks A. castellanii phagocytosis. The effects of Src kinase in the ability of A. castellanii to uptake live non-invasive E. coli strain, HB101. Untreated A. castellanii were used as 100% phagocytosis and levels of phagocytosis in inhibitor-treated A. castellanii are shown as percentage change. Note that Src kinase inhibitor, PP2 but not its inactive analog, PP3 exhibits a significant decrease in A. castellanii phagocytosis at 50 μM (P < 0.05). Results represent the mean of three independent experiments performed in duplicate, bars represent standard error.