Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali

Parasites & Vectors

Table 3 Cattle with failed isometamidium chloride treatment over total treated in south-east Mali (November to December 2007)

Villages	Treatment response 14 days post-treatment			Treatment response 28 days post-treatment¹			Cumulative treatment response²
	*T.c.* ³	*T. v.* ⁴	Total	*T.c.* ³	*T. v.* ⁴	Total
Eastern sector
Kafela	1/4 (25.0)	0/3 (0)	1/7 (14.3) ⁵	1/3 (33.3)	2/3 (66.7)	3/6 (50.0)	4/7 (57.1)
Finibougou	4/7 (57.1)	0/1 (0)	4/8 (50.0)	1/3 (33.3)	0/1 (0.0)	1/4 (25.0)	5/8 (62.5)
Daresalame	4/6 (66.7)	0/1 (0)	4/7 (57.1)	0/2 (0.0)	1/1 (100.0)	1/3 (33.3)	5/7 (71.4)
Ziebougou	3/3 (100.0)	0/3 (0)	3/6 (50.0)	-	0/3 (0.0)	0/3 (0.0)	3/6 (50.0)
Subtotal	12/20 (60.0)	0/8 (0)	12/28 (42.9) ^a	2/8 (25.0)	3/8 (37.5)	5/16 (31.3) ^c	17/28 (60.7) ^d
Western sector
Diassadie	3/9 (33.3)	0/1 (0.0)	3/10 (30.0)	2/6 (33.3)	0/1 (0.0)	2/7 (28.6)	5/10 (50.0)
Waibera	0/7 (0.0)	0/2 (0.0)	0/9 (0.0)	1/7 (14.3)	1/2 (50.0)	2/9 (22.2)	2/9 (22.2)
Kapala	2/5 (40.0)	1/2 (50.0)	3/7 (42.9)	0/3 (0.0)	0/1 (0.0)	0/4 (0.0)	3/7 (42.9)
Tiogola	1/5 (20.0)	1/4 (25.0)	2/9 (22.2)	1/4 (25.0)	1/3 (33.3)	2/7 (28.6)	4/9 (44.4)
Subtotal	6/26 (23.1) ^b	2/9 (22.2)	8/35 (22.9) ^b	4/20 (20.0)	2/7 (28.6)	6/27 (22.2) ^c	14/35 (40.0) ^d
Total	18/46 (39.1)	2/17 (11.8)	20/63 (31.7)	6/28 (21.4)	5/15 (33.3)	11/43 (25.6)	31/63 (49.2)

¹Cattle that were aparasitaemic at day 14 and monitored for trypanosomes at day 28;
²Cumulative treatment response = trypanosome positive cattle at day 14 post-treatment added to those positive 28 days post-treatment;
³ T.c.= Trypanosoma congolense.
⁴ T.v. = Trypanosoma vivax.
⁵Number of cattle with failed treatment over number of cattle treated (percent treatment failure rate).
Different letter superscripts along the column of comparison are significantly (p < 0.05) different.

ISSN: 1756-3305