Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali

Parasites & Vectors

Table 4 Cattle with failed diminazene aceturate treatment over total treated in south-east Mali (November to December 2007)

Villages	Treatment response 14 days post-treatment with 3.5 mg/kg bw. DIM			Response at day 14 post retreatment with 7.0 mg/kg bw. DIM¹
	*T. congolense*	*T. vivax*	Total	*T. congolense*
Eastern sector
Kafela	5/6 (83.3)²	0/1	5/7 (71.4)	2/5 (40.0)
Finibougou	2/7 (28.6)	0/1	2/8 (25.0)	0/2 (0.0)
Daresalame	2/6 (33.3)	0/1	2/7 (14.3)	1/2 (50.0)
Ziebougou	1/2 (50.0)	0/3	1/5 (20.0)	0/1 (0.0)
Subtotal	10/21 (47.6)	0/6 (0)	10/27 (37.0)	3/10 (30.0)
Western sector
Diassadie	2/8 (25.0)	0/1	2/9 (22.2)	0/2 (0.0)
Waibera	2/7 (28.6)	0/2	2/9 (22.2)	1/2 (50.0)
Kapala	3/5 (60.0)	0/2	3/7 (42.9)	1/3 (33.3)
Tiogola	2/4 (50.0)	0/6	2/10 (20.0)	0/2 (0.0)
Subtotal	9/24 (37.5)	0/11 (0)	9/35 (25.7)	2/9 (22.2)
Total	19/45 (42.2)	0/17 (0)	19/62 (30.6)	5/19 (26.3)

¹Retreatment with 7.0 mg/kg bw. DIM was done on cattle that had relapsed trypanosomes 14 days after treatment with 3.5 mg/kg bw. DIM.
²Number of cattle parasitaemic 14 days after treatment over number of cattle treated (treatment failure rate %).

ISSN: 1756-3305