TY - JOUR AU - Wang, Jielin AU - Liu, Xiaolei AU - Jia, Boyin AU - Lu, Huijun AU - Peng, Shuai AU - Piao, Xianyu AU - Hou, Nan AU - Cai, Pengfei AU - Yin, Jigang AU - Jiang, Ning AU - Chen, Qijun PY - 2012 DA - 2012/09/03 TI - A comparative study of small RNAs in Toxoplasma gondii of distinct genotypes JO - Parasites & Vectors SP - 186 VL - 5 IS - 1 AB - Toxoplasma gondii is an intracellular parasite with a significant impact on human health. Inside the mammalian and avian hosts, the parasite can undergo rapid development or remain inactive in the cysts. The mechanism that regulates parasite proliferation has not been fully understood. Small noncoding RNAs (sncRNA) such as microRNAs (miRNAs) are endogenous regulatory factors that can modulate cell differentiation and development. It is anticipated that hundreds of miRNAs regulate the expression of thousands of genes in a single organism. SncRNAs have been identified in T. gondii, however the profiles of sncRNAs expression and their potential regulatory function in parasites of distinct genotypes has largely been unknown. SN - 1756-3305 UR - https://doi.org/10.1186/1756-3305-5-186 DO - 10.1186/1756-3305-5-186 ID - Wang2012 ER -