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Figure 1 | Parasites & Vectors

Figure 1

From: Molecular characterization and ligand binding specificity of the PDZ domain-containing protein GIPC3 from Schistosoma japonicum

Figure 1

Sequence alignment of peptide sequences of SjGIPC3 and GIPC orthologues derived from other species with ClustalX 2.0. Black indicates identity in all variants; grey indicates a conservative substitution in at least one variant; white indicates a non-conservative residue; dashes indicate missing residues. GenBank Accession Numbers: SjGIPC3, Schistosoma japonicum, (AAW24514.1); SmGIPC3, Schistosoma mansoni, (XP_002569948); CsGIPC1, Clonorchis sinensis, (GAA51139); XtGIPC3, Xenopus tropicalis, (NP_001096502); HsGIPC3, Homo sapiens, (NP_573568); XtGIPC1, Xenopus tropicalis, (NP_001011331); HsGIPC1, Homo sapiens, (NP_005707); XtGIPC2, Xenopus tropicalis, (NP_001120269); HsGIPC2, Homo sapiens, (NP_060125); DmKermit, Drosophila melanogaster, (NP_652028); AsGIPC1, Ascaris suum, (ADY44129); CeGIPC1, Caenorhabditis elegans, (NP_498017). The GH1, GH2, and PDZ domains are marked with black boxes and the boundaries for these domains were defined based on the previous study [28]. The “GLGF” motif region within the PDZ domains of GIPC orthologues is highlighted by the red box.

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