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Table 1 List of salivary gland proteins modulated in presence of CHIKV

From: Infection by chikungunya virus modulates the expression of several proteins in Aedes aegypti salivary glands

Protein/function Identification Genebank 3DPI/NI 5DPI/NI
Housekeeping proteins    
Intracellular cell signalling processes    
ran gi|108874624 Nd in NI SG Nd in NI SG
Fibrinogen and fibronectin * gi|108883990 −6 + 2.3
Nucleotide metabolism    
adenosine deaminase gi|108878609   + 2.1
inosine-uridine preferring nucleoside hydrolase * gi|157113519 +2.1/4.6 + 1.9/2.4
Fatty acid metabolism    
cyclohex-1-ene-1-carboxyl-CoA hydratase, putative gi|108880435 +4  
Proteins involved in cytoskeleton    
beta-1 tubulin gi|111035024   −2
Anti-oxydant related    
malic enzyme gi|108883625   −2.3
protein disulfide isomerase gi|157107430   −2
Secreted protease inhibitor    
SERPIN1 protein precursor, putative serpin [Aedes aegypti] 47 kDa gi|108881296   −10
SERPIN1 protein precursor, putative serpin 41 kDa gi|108881297   + 2.7
putative serpin * gi|18568304 + 2 + 2 .3
Immunity related protein    
Angiopoietin-like protein variant [Aedes aegypti]° gi|94468352 +4.5  
Blood feeding    
Apyrase, putative [Aedes aegypti]* gi|157113141 + 3.2/3.4 + 1.9/2.2/2.5
30 kDa salivary gland allergen Aed a 3 [Aedes aegypti]* gi|2114497 −3 + 3
putative 30 kDa allergen-like protein gi|18568322   Nd in NI SG
Unknown    
Antifreeze protein, putative [Aedes aegypti] gi|157103422 + 2.2 + 1.9
Venom allergen [Aedes aegypti] gi|18568284   + 4.1
putative 16.9 kDa secreted protein gi|18568330 + 1.9  
Putative 34 kDa family secreted salivary protein gi|94468642 +2.1/7 + 2.1/2.2
62 kDa family gi|108883987   + 1.9
Conserved hypothetical protein gi|108880897   +2
Conserved hypothetical protein gi|108883988 +2.2/4 +2
short salivary D7 protein gi|157115994 +1.9 +2.5
  1. *proteins for which a modulation of gene expression was observed in dengue-infected salivary glands, ° proteins for which a modulation of gene expression was observed in blood-fed salivary glands, SG: salivary glands, Nd: not detected, NI: non infected.