Table 1 List of salivary gland proteins modulated in presence of CHIKV

Housekeeping proteins

Intracellular cell signalling processes

ran

gi|108874624

Nd in NI SG

Nd in NI SG

Fibrinogen and fibronectin *

gi|108883990

−6

+ 2.3

Nucleotide metabolism

adenosine deaminase

gi|108878609

+ 2.1

inosine-uridine preferring nucleoside hydrolase *

gi|157113519

+2.1/4.6

+ 1.9/2.4

Fatty acid metabolism

cyclohex-1-ene-1-carboxyl-CoA hydratase, putative

gi|108880435

+4

Proteins involved in cytoskeleton

beta-1 tubulin

gi|111035024

−2

Anti-oxydant related

malic enzyme

gi|108883625

−2.3

protein disulfide isomerase

gi|157107430

−2

Secreted protease inhibitor

SERPIN1 protein precursor, putative serpin [Aedes aegypti] 47 kDa

gi|108881296

−10

SERPIN1 protein precursor, putative serpin 41 kDa

gi|108881297

+ 2.7

putative serpin *

gi|18568304

+ 2

+ 2 .3

Immunity related protein

Angiopoietin-like protein variant [Aedes aegypti]°

gi|94468352

+4.5

Blood feeding

Apyrase, putative [Aedes aegypti]*

gi|157113141

+ 3.2/3.4

+ 1.9/2.2/2.5

30 kDa salivary gland allergen Aed a 3 [Aedes aegypti]*

gi|2114497

−3

+ 3

putative 30 kDa allergen-like protein

gi|18568322

Nd in NI SG

Unknown

Antifreeze protein, putative [Aedes aegypti]

gi|157103422

+ 2.2

+ 1.9

Venom allergen [Aedes aegypti]

gi|18568284

+ 4.1

putative 16.9 kDa secreted protein

gi|18568330

+ 1.9

Putative 34 kDa family secreted salivary protein

gi|94468642

+2.1/7

+ 2.1/2.2

62 kDa family

gi|108883987

+ 1.9

Conserved hypothetical protein

gi|108880897

+2

Conserved hypothetical protein

gi|108883988

+2.2/4

+2

short salivary D7 protein

gi|157115994

+1.9

+2.5