Table 3 GO analysis of the target genes of the differentially expressed miRNAs in different tissues of Wistar rats following S. japonicum infection
Up-regulated | Down-regulated |
|---|---|
Biological process | |
Intracellular signaling cascade | Chordate embryonic development |
Negative regulation of macromolecule metabolic process | Embryonic development ending in birth or egg hatching |
Phosphate metabolic process | Homeostatic process |
Phosphorus metabolic process | Metal ion transport |
Phosphorylation | Positive regulation of transcription from RNA polymerase II promoter |
Cell component | |
Cell projection part | Cytoplasmic membrane-bounded vesicle |
Cytoskeletal part | Cytoplasmic vesicle |
Cytoskeleton | Endomembrane system |
Extrinsic to membrane | Endosome |
Intracellular non-membrane-bounded organelle | Golgi apparatus |
Membrane fraction | Internal side of plasma membrane |
Microtubule | Intrinsic to plasma membrane |
Microtubule cytoskeleton | Membrane-bounded vesicle |
Non-membrane-bounded organelle | Postsynaptic membrane |
Transcription factor complex | Vesicle |
Molecular function | |
Cytoskeletal protein binding | Channel activity |
Identical protein binding | Nucleotide binding |
Protein dimerization activity | Passive transmembrane transporter activity |