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Table 1 Estimated overall parasite load of L. infantum -infected BALB/c mice 2 and 6 weeks post-infection

From: Characterization of the biology and infectivity of Leishmania infantum viscerotropic and dermotropic strains isolated from HIV+ and HIV- patients in the murine model of visceral leishmaniasis

Total parasite load

2 weeks post-infection

6 weeks post-infection

 

Bibiano

E390M

HL

ST

Bibiano

E390M

HL

ST

Spleen

67.7 × 104

8.82 × 104

44.1 × 104

3.81 × 104

62.7 × 104

0.40 × 104

329 × 104

18.9 × 104

Liver

157 × 106

2.77 × 106

112 × 106

0.14 × 106

0.35 × 106

2.54 × 106

86.8 × 106

2.42 × 106

Bone marrow

15.0 × 107

4.49 × 107

11.9 × 107

50.9 × 107

13.9 × 107

2.29 × 107

18.1 × 107

11.7 × 107

Lymph nodes

4.83 × 104

0.19 × 104

67.0 × 104

0.10 × 104

1.78 × 104

0.015 × 104

10.3 × 104

0.59 × 104

Blood

0.97 × 103

0.42 × 103

19.4 × 103

0.32 × 103

6.54 × 103

3.12 × 103

1.95 × 103

4.53 × 103

Whole animal

3.08 × 108

0.48 × 108

2.32 × 108

5.09 × 108

1.40 × 108

0.25 × 108

2.71 × 108

1.19 × 108

  1. Mean weights of spleen, liver and inguinal lymph nodes of the infected animals (Additional file 6: Figure S5) were used in these calculations. Values for total volume of blood (1.8 mL) and total number of bone marrow cells (4.5 × 108) were estimated as published elsewhere [40, 41].
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Parasites & Vectors

ISSN: 1756-3305

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