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Table 2 Classifiers’ true positive rates for different false positive rates

From: Identification of novel arthropod vector G protein-coupled receptors

Classifier

True Positive Rate (TPR)*

 
 

GPCRHMM’s FPR (0.0061)

PredCouple’s FPR (0.0066)

Pfam’s FPR (0.0067)

FPR where Ensemble*’s TPR plateaus (0.01)

Best for all FPRs ≤ 0.01

Ensemble*

87%

89%

89%

91%

91%

GPCRHMM

81%

--

--

--

81%

GPCRHMM*

81%

81%

81%

83%

83%

Pfam

--

--

82%

--

82%

Pfam*

80%

80%

80%

80%

80%

PredCouple

--

86%

--

--

86%

  1. *Percentage of training set GPCRs correctly predicted (true positive rates) for fixed percentages of sequences misclassified as GPCRs (false positive rates) are given. The false positive rates (FPR) of GPCRHMM, PredCouple, Pfam, and at which Ensemble*’s true positive rate plateaus were chosen to provide the most direct comparisons between the classifiers.