Table 1 Effects of 5 weeks treatment with telmisartan (TELM) given either alone or combined with praziquantel (PZQ) on hepatomesenteric worm load and oogram pattern (% egg developmental stages) of mice infected with Schistosoma mansoni and sacrificed at the 10 ^th (set 1) and 15 ^th (set 2) weeks post infection

Hepatomesenteric worm load

Male

5.25±0.12

5.75±0.51

1.17±0.08*^@

0.72±0.03*^@

3.86±0.28

4.56±0.06

0.63±0.03* ^@

1.10±0.09* ^@

Female

1.75±0.13

1.88±0.04

0.17±0.01*^@

0.14±0.01*^@

1.86±0.11

1.67±0.13

0.00±0.00*^@

0.00±0.00*^@

Couple

4.00±0.41

3.25±0.37

0.00±0.00*^@

0.00±0.00*^@

3.72±0.08

3.56±0.18

0.00±0.00*^@

0.00±0.00*^@

Total

15.00±1.08

14.25±0.88

1.33±0.12*^@

0.86±0.03*^@

12.57±0.65

12.56±0.41

0.63±0.03*^@

1.10±0.08*^@

% Egg developmental stages

Immature

48.00±2.00

52.13±0.74

0.00±0.00*^@

0.00±0.00*^@

40.57±0.61

38.67±1.29

0.00±0.00*^@

0.00±0.00*^@

Mature

44.75±1.93

41.00±0.54

4.17±2.00*^@

3.29±0.01*^@

36.57±1.11

35.22±1.73

1.00±0.05*^@

0.70±0.02*^@

Dead

7.25±0.02

6.88±0.48

95.83±2.01*^@

96.72±0.72*^@

19.58±1.56

20.33±0.67

99.13±0.44*^@

98.60±0.65*^@