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Table 2 NCBI accession numbers (number.version) of nucleotide-sugar transporter genes referenced in this study

From: In silico analysis of the fucosylation-associated genome of the human blood fluke Schistosoma mansoni: cloning and characterization of the enzymes involved in GDP-L-fucose synthesis and Golgi import

Source organism (tree prefix) a

Gene identifier b

Nt accession

Prot. accession

NST Substrate(s) c

References

Homo sapiens (Hs)

SLC35C1

NM_018389.4

NP_060859.4

GDP-L-Fuc

[21, 27, 28, 54]

 

SLC35B4

NM_032826.4

NP_116215.1

UDP-Xyl, UDP-GlcNAc

[55]

 

SLC35A3/hUGlcNAcT

NM_012243.1

NP_036375.1

UDP-GlcNAc

[56]

 

SLC35D2/hUGTrel8/HFRC1

NM_007001.2

NP_008932.2

UDP-Glc, UDP-GlcNAc, GDP-Man

[57]

 

hUGTrel7

AB044343.1

BAB18586.1

UDP-GlcA, UDP-GalNAc

[58]

 

hUGT1

D84454.1

BAA12673.1

UDP-Gal, UDP-GalNAc

[5962]

Canis lupus (Cl)

SLC35A3

NM_001003385.1

NP_001003385.1

UDP-GlcNAc

[63]

 

SLC35A2

NM_001003059.2

NP_001003059.2

UDP-Gal

[64]

Mus musculus (Mm)

Slc35c1

NM_211358.2

NP_997597.1

GDP-L-Fuc

[30, 65]

 

Slc35b4

NM_021435.3

NP_067410.1

UDP-Xyl, UDP-GlcNAc

[66]

 

mUGT1

AB027147.1

BAA86885.1

UDP-Gal

[67]

 

Slc35a1

NM_011895.3

NP_036025.2

CMP-Sia

[68]

Cricetulus griseus (Cgr)

Slc35a1

NM_001246755.1

NM_001246755.1

CMP-Sia

[69]

Drosophila melanogaster (Dm)

Gfr

NM_141525.1

NP_649782.1

GDP-L-Fuc

[70, 71]

 

Efr

NM_132071.1

NP_572299.1

" "

[72]

 

Frc

AB062677.1

BAB62105.1

UDP-GlcA, UDP-GalNAc, UDP-Gal, UDP-GlcNAc, UDP-Xyl

[73, 74]

 

ugt

AB055493.1

BAB62747.1

UDP-Gal, UDP-GalNAc

[62, 75]

Caenorhabditis elegans (Ce)

C50F4.14

AF323969.1

AAK50396.1

GDP-L-Fuc

[28]

 

SQV-7

NM_063035.4

NP_495436.1

UDP-GlcA, UDP-GalNAc, UDP-Gal

[76]

Schistosoma mansoni (Sm)

GFT

GU574756.1

ADO17519.1

GDP-L-Fuc (putative)

Present study

Leishmania donovani (Ld)

LPG2

U26175.1

AAC46914.1

GDP-Man, GDP-Ara, GDP-Fuc

[77]

Cryptococcus neoformans (Cn)

GMT1

XM_571496.1

XP_571496.1

GDP-Man

[78]

 

GMT2

XM_571874.1

XP_571874.1

" "

" "

Saccharomyces cerevisiae (Sc)

YEA4

NM_001178819.1

NP_010912.1

UDP-GlcNAc

[79]

Candida albicans (Ca)

VRG4

AF164627.1

AAK74075.1

GDP-Man

[80]

Candida glabrata (Cgl)

Vrg4

AF360395.1

AAK51897.1

GDP-Man

[81]

Arabidopsis thaliana (At)

GONST1

AJ314836.1

CAC69066.1

GDP-Man

[82, 83]

 

GONST2

NM_100603.5

NP_172209.4

" "

[83]

 

AtUTr1

AY115566.1

AAM48281.1

UDP-Gal, UDP-Glc

[84]

 

NST-K1

NM_179196.1

NP_849527.1

UDP-Gal

[85]

 

udpgalt1

AJ633720.1

CAG18176.1

" "

[86]

 

udpgalt2

AJ633721.1

CAG18177.1

" "

" "

  1. a “tree prefix” refers to nomenclature applied in phylogenetic analyses of NSTs (Figure 6, in Additional file 3: Figure S2).
  2. b Official gene names/identifiers are provided. Genes in boldface type were used as query sequences to search for GDP-L-fucose transporter homologs in the SchistoDB [35].
  3. c NST activity has been demonstrated for these substrates. GDP-Fuc, GDP-L-fucose; UDP-Xyl, UDP-D-xylose; UDP-GlcNAc, UDP-D-N-acetylglucosamine; UDP-Glc, UDP-D-glucose; UDP-GlcA, UDP-D-glucuronic acid; UDP-GalNAc, UDP-D-N-acetylgalactosamine; UDP-Gal, UDP-D-galactose; GDP-Man, GDP-D-mannose; CMP-Sia, CMP-sialic acid; GDP-Ara, GDP-D-arabinose.