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Table 1 Prevalence of sepsis in filariasis infected subjects

From: Decreased prevalence of sepsis but not mild or severe P. falciparum malaria is associated with pre-existing filarial infection

Subjects Sepsis (n=89) Healthy control (n=38) P value
  CFA+ve CFA-ve CFA+ve CFA-ve  
Number (%) *6 (6.7) 83 (93.3) *16 (42.2) 22 (57.8) CFA+ve in sepsis vs HC (<0.0001), CFA-ve vs in sepsis vs HC(<0.0001)
Sex(M/F) 6/0 55/28 9/7 10/12 -
Mean Age in years(range) 42.83(24–73) 46.24(17–85) 31.22(20–75) 29.85(12–69) -
APACHE II score 14.25 ± 4.15 12.63 ± 0.58 - - CFA+ve vs CFA-ve, NS
Mechanical ventillaion 2 (33.34) 7 (8.43) - - CFA+ve vs CFA-ve, NS
Vasopressors 2 (33.34) 18 (21.6) - - CFA+ve vs CFA-ve, NS
Total leukocyte count (10 3 /mm 3 ) 13.4-30 7.2-150 ND ND CFA+ve vs CFA-ve, NS
CRP (mean±SD) mg/ml (Range) 86.92 ± 34.10 (16.33-146.6) 97.17±5.18 (10.42-150.8) ND ND CFA+ve vs CFA-ve, NS
  1. NOTE: CFA; circulating filarial antigen.*p value<0.0001, 95% Confidence Interval, Odds ratio = 0.099. Data are no. (%) of participants unless otherwise specified.