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Table 1 IC 50 values of Newly excysted larvae (NEL) and adult E. caproni following treatment with praziquantel, tribendimidine, albendazole and quinine

From: Development of an in vitro drug sensitivity assay based on newly excysted larvae of Echinostoma caproni

Drug

NEL assay

Adult worm assay

IC50(μg/ml)

R- value

IC50(μg/ml)

R- value

Praziquantel

0.19

0.94

0.06

0.77

Tribendimidine

0.35

0.93

2.93

0.91

Albendazole

2.03

0.99

26.71

0.82

Quinine

n.d.

n.d.

n.d.

n.d.

  1. IC50 values were calculated 72 hrs post exposure. R-value represents the goodness of fit. N.d. means the data for that drug did not produce a curve from which an IC50 value could be derived.