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Table 2 The spleeno-somatic and hepato-somatic indices of BALB/c infected with L. major , S. mansoni and those co-infected with L. major+S. mansoni undergoing various treatments with Pentostam and PZQ between week 8 and week 10

From: Combination therapy using Pentostam and Praziquantel improves lesion healing and parasite resolution in BALB/c mice co-infected with Leishmania major and Schistosoma mansoni

Infection Drug administration Spleeno-somatic index Hepato-somatic index
L. major   Week 8 Week 10 Week 8 Week 10
  P 0.77 ± 0.031 0.74 ± 0.039 4.45 ± 0.14 3.92 ± 0.08
  PZQ 1.11 ± 0.173 1.45 ± 0.100 4.67 ± 0.15 5.18 ± 0.23
  P + PZQ 0.81 ± 0.016 0.74 ± 0.029 4.25 ± 0.18 3.81 ± 0.13
  PBS 1.03 ± 0.150 1.67 ± 0.084 4.57 ± 0.10 5.97 ± 0.32
S. mansoni P 1.11 ± 0.088 1.49 ± 0.066 8.83 ± 1.11 10.19 ± 0.50
  PZQ 0.94 ± 0.073 0.96 ± 0.064 4.61 ± 0.09 4.14 ± 0.21
  P + PZQ 0.86 ± 0.081 0.79 ± 0.044 4.46 ± 0.07 4.04 ± 0.22
  PBS 1.09 ± 0.081 1.72 ± 0.073 5.87 ± 1.12 7.66 ± 0.27
L. major+ P 1.11 ± 0.165 1.37 ± 0.076 7.83 ± 1.44 8.68 ± 2.04
S. mansoni PZQ 1.20 ± 0.111 1.41 ± 0.077 8.64 ± 0.12 9.47 ± 0.13
  P + PZQ 1.03 ± 0.075 1.01 ± 0.041 4.46 ± 0.11 4.19 ± 0.07
  PBS 1.17 ± 0.046 1.88 ± 0.051 5.81 ± 0.16 7.50 ± 0.43