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Table 3 Worm counts of BALB/c infected with S. mansoni and those co-infected with L. major+S. mansoni under various treatments with Pentostam and PZQ between week 8 and week 10

From: Combination therapy using Pentostam and Praziquantel improves lesion healing and parasite resolution in BALB/c mice co-infected with Leishmania major and Schistosoma mansoni

Infection Drug administration Week 8 Week 10
S. mansoni P 34.80 ± 6.09 41.2 ± 2.58
  PZQ 10.4 ± 1.29 8.4 ± 1.50
  P + PZQ 14.4 ± 1.24 11.60 ± 1.24
  PBS 36.20 ± 5.17 46 ± 2.79
L. major + S. mansoni P 30.60 ± 7.59 38.6 ± 2.68
  PZQ 11.40 ± 2.74 8.80 ± 1.44
  P + PZQ 7.40 ± 2.60 5.0 ± 1.20
  PBS 34.20 ± 3.14 44.2 ± 2.37
Friedman Two-Way ANOVA Main effect   
  F 11.231 19.258
  P-value 0.0002 0.0000
  Repeated measure   
  F   7.511
  P-value   0.0014