Table 3 Worm counts of BALB/c infected with S. mansoni and those co-infected with L. major + S. mansoni under various treatments with Pentostam and PZQ between week 8 and week 10

S. mansoni

P

34.80 ± 6.09

41.2 ± 2.58

PZQ

10.4 ± 1.29

8.4 ± 1.50

P + PZQ

14.4 ± 1.24

11.60 ± 1.24

PBS

36.20 ± 5.17

46 ± 2.79

L. major + S. mansoni

P

30.60 ± 7.59

38.6 ± 2.68

PZQ

11.40 ± 2.74

8.80 ± 1.44

P + PZQ

7.40 ± 2.60

5.0 ± 1.20

PBS

34.20 ± 3.14

44.2 ± 2.37

Friedman Two-Way ANOVA

Main effect

F

11.231

19.258

P-value

0.0002

0.0000

Repeated measure

F

7.511

P-value

0.0014