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Table 3 Effect of albendazole, nitazoxanide, sequentially administered albendazole-nitazoxanide combination, and placebo against intestinal protozoa infections among school-aged children on Pemba Island in mid-2011

From: Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide

Characteristic Single-dose albendazole Single-dose nitazoxanide Nitazoxanide-albendazole combination Placebo
G. intestinalis
No. of infected children 25 21 19 25
No. of children not cured after treatment 10 9 11 12
CR, % (95% CI) 60.0 57.1 42.1 52.0
  (39.4–80.6) (34.1–80.2) (17.7–66.6) (31.0–73.0)
E. histolytica/E. dispar
No. of infected children 23 23 31 22
No. of children not cured after treatment 10 9 10 10
CR, % (95% CI) 56.5 60.9 67.7 54.5
  (34.6–78.4) (39.3–82.4) (50.3–85.2) (31.9–77.1)
B. hominis
No. of infected children 35 37 33 49
No. of children not cured after treatment 15 16 10 16
CR, % (95% CI) 57.1 56.8 69.7 67.3
  (39.9–74.4) (40.0–73.5) (53.1–86.2) (53.7–81.0)
E. coli
No. of infected children 75 82 56 70
No. of children not cured after treatment 50 38 27 50
CR, % (95% CI) 33.3 53.7 51.8 28.6
  (22.4–44.3) (42.6–64.7) (38.3–65.3) (17.7–39.4)
E. hartmanni
No. of infected children 14 22 18 19
No. of children not cured after treatment 5 5 4 7
CR, % (95% CI) 64.3 77.3 77.8 63.2
  (35.6–93.0) (58.3–96.3) (56.5–99.1) (39.3–87.0)
E. nana
No. of infected children 24 25 23 35
No. of children not cured after treatment 10 9 2 15
CR, % (95% CI) 58.3 64.0 91.3 57.1
  (37.1–79.6) (43.8–84.2) (78.8–100.0) (39.9–74.4)
C. mesnili
No. of infected children 17 10 6 12
No. of children not cured after treatment 4 1 1 5
CR, % (95% CI) 76.5 90.0 83.3 58.3
  (54.0–99.0) (67.4–100.0) (40.5–100.0) (25.6–91.1)
I. bütschlii
No. of infected children 5 13 8 11
No. of children not cured after treatment 1 2 2 4
CR, % (95% CI) 80.0 84.6 75.0 63.6
  (24.5–100.0) (61.9–100.0) (36.3–100.0) (29.7–97.5)
  1. CI, confidence interval; CR, cure rate.