Table 2 Estimated cure rates of three different treatment regimens against Clonorchis sinensis infection, according to different diagnostic approaches
Diagnostic approach | Observed cure rate [% (95% CI)] | ||
|---|---|---|---|
Praziquantel (75 mg/kg divided in 3 doses) | Tribendimidine (400 mg once daily for 3 days) | Tribendimidine (400 mg once) | |
Single Kato-Katz | 72.0 (50.6-87.9) | 75.0 (53.3-90.2) | 60.0 (38.7-78.9) |
Triplicate Kato-Katz | 60.0 (38.7-78.9) | 66.7 (44.7-84.4) | 56.0 (34.9-75.6) |
Six Kato-Katz | 56.0 (34.9-75.6) | 58.3 (36.6-77.9) | 44.0 (24.4-65.1) |
Single FECT | 84.0 (63.9-95.5) | 87.5 (67.6-97.3) | 76.0 (54.9-90.6) |
Duplicate FECT | 80.0 (59.3-93.2) | 79.2 (57.8-92.9) | 72.0 (50.6-87.9) |
Diagnostic ‘gold’ standarda | 52.0 (31.3-72.2) | 50.0 (29.1-70.9) | 44.0 (24.4-65.1) |