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Figure 8 | Parasites & Vectors

Figure 8

From: Induction of long-lasting protective immunity against Toxoplasma gondii in BALB/c mice by recombinant surface antigen 1 protein encapsulated in poly (lactide-co-glycolide) microparticles

Figure 8

Survival of immunized mice after a lethal tachyzoite challenge. Groups of mice were intraperitoneally immunized twice with PLG-rSAG1 microparticles (■ ), rSAG1 (Vet L-10) ( ), soluble rSAG1 alone (□ ), PLG ( ), or PBS ( ). Eight weeks after boosting, five groups of 10 mice each were subcutaneously infected with 1×104 live tachyzoites of T. gondii (RH strain). Animals were observed daily for an additional month (28 days) and the final survival rates were calculated. *P<0.05 when comparing the PLG-rSAG1 group to the rSAG1 (Vet L-10) group.

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