Treatment group | # dogs/cats | | Days post-treatment1 |
---|
| | | Day 0 | Day 7 | Day 14 | Day 21 | Day 28 – 30 | Day 40 - 45 | Day 54 - 60 |
---|
Indoxacarb2 | 32/3 | Geomean4 | 51.0a | 1.1a | 0.6a | 1.3a | 2.6a | 0.3a | 0.5a |
| % control5 | | 97.8 | 98.8 | 97.4 | 95.0 | 99.4 | 99.1 |
| % (#) pets with no fleas | 0.0 | 48.6 | 71.4 | 40.0 | 20.0 | 71.4 | 77.1 |
(0/35) | (17/35) | (25/35) | (14/35) | (7/35) | (25/35) | (27/35) |
Fipronil (s)-methoprene3 | 30/2 | Geomean | 28.1a | 4.1b | 6.4b | 13.6b | 14.2b | 8.0b | 12.7b |
| % control | | 85.5 | 77.3 | 51.5 | 49.5 | 71.6 | 54.8 |
| % (#) pets with no fleas | 0.0 | 15.6 | 15.6 | 9.4 | 6.3 | 21.9 | 15.6 |
| | | (0/32) | (5/32) | (5/32) | (3/32) | (2/32) | (7/32) | (5/32) |
- 1Dogs and cats treated on day 0 and again between days 28 – 30.
- 2Dogs and cats were treated topically with indoxacarb (19.53% w/w; ACTIVYL® Merck Animal Health) according to label directions.
- 3Dogs were treated topically with fipronil (9.8% w/w)–(s)-methoprene (8.8% w/w) spot-on (Frontline®Plus; Merial) and cats were treated topically with fipronil (9.8% w/w)–(s)-methoprene (11.8% w/w) (Frontline®Plus; Merial) according to label directions.
- 4Geometric mean numbers of fleas in visual area counts on pets.
- 5{(Day 0 geometric mean animal area flea counts – day x geometric mean animal area flea counts)/day 0 geometric mean animal area flea counts)} x 100
- a,bGeometric means in a column with unlike letter superscripts are significantly different (P values ≤0.0079).