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Table 2 Geometric mean and percent control of fleas recovered in premises flea traps in naturally infested homes when dogs and cats were treated with indoxacarb or fipronil (s)-methoprene based topical spot-on formulations

From: Evaluation of indoxacarb and fipronil (s)-methoprene topical spot-on formulations to control flea populations in naturally infested dogs and cats in private residences in Tampa FL. USA

Treatment group # homes completing study   Days post-treatment1
    Day 0 Day 7 Day 14 Day 21 Day 28 – 30 Day 40 - 45 Day 54 – 60
Indoxacarb2 18 Geomean4 29.4a 8.1a 5.2a 3.8a 3.5a 0.9a 0.7a
  % control5   72.4 82.4 87.2 87.9 97.0 97.7
Fipronil (s)-methoprene3 19 Geomean 25.5a 9.5a 7.5a 7.0a 10.1a 5.1b 3.9b
  % control   62.6 70.4 72.4 60.3 79.9 84.6
  1. 1Dogs and cats treated on day 0 and again between days 28 – 30.
  2. 2Dogs and cats were treated topically with indoxacarb (19.53% w/w; ACTIVYL® Merck Animal Health) accordingly to label directions.
  3. 3Dogs were treated topically with fipronil (9.8% w/w)–(s)-methoprene (8.8% w/w) spot-on (Frontline®Plus; Merial) and cats were treated topically with fipronil (9.8% w/w)–(s)-methoprene (11.8% w/w) (Frontline®Plus; Merial) according to label directions.
  4. 4Geometric mean numbers of fleas recovered in two intermittent light flea traps.
  5. 5{(Day 0 geometric mean trap flea counts – day x geometric mean trap flea counts)/day 0 geometric mean trap flea counts)} x 100
  6. a,bGeometric means in a column with unlike letter superscripts are significantly different (P values ≤0.0054).