Figure 5From: Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophagesActivation of MAPKs (ERK, p38 and JNK) by Leishmania LPG in BALB/c peritoneal macrophages. Mouse peritoneal macrophages were stimulated for 45 min with 10 μg/mL of LPG from L. infantum (A, C and E) and L. braziliensis (B, D and F). Dually phosphorylated MAPKs were detected by western blot. C, negative control; LPGb, L. braziliensis LPG and LPGi, L. infantum LPG. Total p38 (A to F) content was used as a normalizing protein.Back to article page