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Figure 6 | Parasites & Vectors

Figure 6

From: Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages

Figure 6

LPGs purified from Leishmania infantum and Leishmania braziliensis induce translocation of NFkB through TLRs. CHO cells expressing TLR2 (TLR2+), TLR4 (TLR4+), or neither (TLR2-/TLR4-) were either untreated (gray line) or exposed (black line) to LPS, Staphylococcus aureus (SA), L. infantum LPG (LPGi) or L. braziliensis LPG (LPGb), as indicated. CD25 expression was measured by flow cytometry 18 h after stimulation. Percentage = percentage of CD25 expression on stimulated cells minus percentage of CD25 expression on non-stimulated cells.

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Parasites & Vectors

ISSN: 1756-3305

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