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Table 1 Comparison of diagnostic test sensitivity

From: A multicentric evaluation of the recombinant Leishmania infantum antigen-based immunochromatographic assay for the serodiagnosis of canine visceral leishmaniasis

Serum sample Comparison of diagnostic test sensitivity (95% CI) [n/N]
Source EIE®LVC DPP® LVC DPP rLci1A DPP rLci2B DPP rLci1A/rLci2B DPP® LVC + DPPrLci1A/rLci2B
BA 98% 92.5% 66% 81.1% 83% 96.2%
(86–100) (82–97) (53–77) (69–89) (71–91) (87–99)
[49/50] [49/53] [35/53] [43/53] [44/53] [51/53]
MG 93.5% 84% 70% 76% 84% 88%
(92–100) (72–92) (56–81) (63–86) (72–92) (76–94)
[43/46] [42/50] [35/50] [38/50] [42/50] [44/50]
RN 100% 88.2% 90.2% 90.2% 94.1% 96%
(93–100) (77–95) (79–96) (79–96) (84–98) (87–99)
[51/51] [45/51] [46/51] [46/51] [48/51] [49/51]
Total* 97.3% 88.3% 75.3% 82.5% 87% 93.5%
  (93–99) (82–93) (68–82) (76–88) (81–91) (89–96)
  [143/147**] [136/154] [116/154] [127/154] [134/154] [144/154]
  1. Abbreviations: CI = confidence interval, n = number of sera that tested positive, N = number of sera evaluated.
  2. *154 canine serum samples tested positive for VL in culture and were obtained from three participating INCT-DT laboratories.
  3. **7 out of 154 canine serum samples were not considered under ELISA due to inconclusive test results.