Serum sample
|
Comparison of diagnostic test sensitivity (95% CI) [n/N]
|
---|
Source
|
EIE®LVC
|
DPP® LVC
|
DPP rLci1A
|
DPP rLci2B
|
DPP rLci1A/rLci2B
|
DPP® LVC + DPPrLci1A/rLci2B
|
---|
BA
|
98%
|
92.5%
|
66%
|
81.1%
|
83%
|
96.2%
|
(86–100)
|
(82–97)
|
(53–77)
|
(69–89)
|
(71–91)
|
(87–99)
|
[49/50]
|
[49/53]
|
[35/53]
|
[43/53]
|
[44/53]
|
[51/53]
|
MG
|
93.5%
|
84%
|
70%
|
76%
|
84%
|
88%
|
(92–100)
|
(72–92)
|
(56–81)
|
(63–86)
|
(72–92)
|
(76–94)
|
[43/46]
|
[42/50]
|
[35/50]
|
[38/50]
|
[42/50]
|
[44/50]
|
RN
|
100%
|
88.2%
|
90.2%
|
90.2%
|
94.1%
|
96%
|
(93–100)
|
(77–95)
|
(79–96)
|
(79–96)
|
(84–98)
|
(87–99)
|
[51/51]
|
[45/51]
|
[46/51]
|
[46/51]
|
[48/51]
|
[49/51]
|
Total*
|
97.3%
|
88.3%
|
75.3%
|
82.5%
|
87%
|
93.5%
|
|
(93–99)
|
(82–93)
|
(68–82)
|
(76–88)
|
(81–91)
|
(89–96)
|
|
[143/147**]
|
[136/154]
|
[116/154]
|
[127/154]
|
[134/154]
|
[144/154]
|
- Abbreviations: CI = confidence interval, n = number of sera that tested positive, N = number of sera evaluated.
- *154 canine serum samples tested positive for VL in culture and were obtained from three participating INCT-DT laboratories.
- **7 out of 154 canine serum samples were not considered under ELISA due to inconclusive test results.