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Table 2 Key characteristics of six different diagnostic methods

From: Field comparison of circulating antibody assays versus circulating antigen assays for the detection of schistosomiasis japonica in endemic areas of China

Assay Tested samples Positive samples Adjusted prevalence (%) [95% CI] Detection target Solid phase Time required per sample Volume of sample Extra supplies*
IHA 1864 240 12.9 [11.38-14.42] Anti-SEA antibody Red blood cells from sheep 40 min 25 μl Yes
ELISA 1864 240 12.9 [11.38-14.42] Anti-SEA antibody Microtitre plate 90 min 1 μl Yes
DDIA 1864 231 12.4 [10.90-14.90] Anti-SEA antibody Nitrocellulose membrane 15 min 10 μl No
ELISA (COM) 1864 87 4.7 [3.74-5.66] Circulating antigen Microtitre plate 90 min 50 μl Yes
ELISA (IgY) 1864 81 4.3 [3.40-5.22] Circulating antigen Microtitre plate 90 min 20 μl Yes
Kato-Katz 1864 28 1.5 Egg Plastic template 40 min 41.7 mg Yes
  1. *Additional equipment required for all serological tests consisted of handheld micropipettes and micropipette tips.