Figure 6From: Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicummiR-454 was down-regulated in S. japonicum -infected fibrotic livers. (A) The expression of the miR-454 was down-regulated in the fibrotic tissues infected with S. japonicum for 8 weeks as detected by qRT-PCR. * P <0.05 vs control (normal mice). (B) The levels of α-SMA and Smad4 expression were all up-regulated in the fibrotic livers infected with S. japonicum for 8 weeks as determined by Western blot.Back to article page