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Table 5 Enrichment of InterPro protein domains among alternatively spliced isogroups

From: Identification and characterization of alternative splicing in parasitic nematode transcriptomes

InterPro protein domain

Number of species with domain

Total number of Isogroups containing domain

Percentage of isogroups with domain that are AS*

P value for enrichment**

IPR000504

RNA recognition motif domain

9

858

50.7%

2.1E-06

IPR016197

Chromo domain-like

9

128

64.1%

3.8E-05

IPR012677

Nucleotide-binding, alpha-beta plait

9

1037

48.7%

4.2E-05

IPR006092

Acyl-CoA dehydrogenase, N-terminal

8

53

73.6%

2.0E-04

IPR013786

Acyl-CoA dehydrogenase/oxidase, N-terminal

9

68

69.1%

3.2E-04

IPR003593

AAA + ATPase domain

8

189

57.7%

3.6E-04

IPR001412

Aminoacyl-tRNA synthetase, class I, conserved site

8

43

74.4%

6.6E-04

IPR006091

Acyl-CoA oxidase/dehydrogenase, central domain

9

70

67.1%

7.6E-04

IPR009100

Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain

9

93

63.4%

8.9E-04

IPR011993

Pleckstrin homology-like domain

9

474

50.4%

1.7E-03

IPR014001

Helicase, superfamily 1/2, ATP-binding domain

9

317

52.1%

3.7E-03

IPR023780

Chromo domain

9

79

63.3%

3.6E-03

IPR000953

Chromo domain/shadow

9

85

62.4%

3.7E-03

IPR015421

Pyridoxal phosphate-dependent transferase, major region, subdomain 1

9

275

52.7%

3.8E-03

IPR002194

Chaperonin TCP-1, conserved site

8

55

67.3%

3.6E-03

IPR003954

RNA recognition motif domain, eukaryote

9

41

70.7%

4.5E-03

IPR006020

PTB/PI domain

9

71

63.4%

5.7E-03

IPR001650

Helicase, C-terminal

9

298

51.7%

6.8E-03

IPR017998

Chaperone tailless complex polypeptide 1 (TCP-1)

9

66

63.6%

7.6E-03

IPR011545

DNA/RNA helicase, DEAD/DEAH box type, N-terminal

9

275

52.0%

7.3E-03

IPR002495

Glycosyl transferase, family 8

7

11

90.9%

7.2E-03

  1. *In total, 40.5% of all isogroups associated with any InterPro domain are AS.
  2. **Binomial test, FDR corrected, threshold value of 0.01.